Tapatio is the preferred mainstream hot sauce. Better than Tabasco and Cholula by a mile. A lot of white people tend to go for Cholula because they think it's more authentic or something, but it's definitely not.
Cholula's bottle is definitely cooler though.
I enjoy quite a few hot sauces, but I'm not looking for mouth pain, I'm after flavor. If it makes my nose run and my face red, but it tastes great, I'm on board. There's a few solid Louisiana hot sauces I have fairly often and I can't remember what the hell they're called because they're at a Lousiana-style restaurant I go to. I'll be back with the name in case you guys want to try them.